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50 Signs of Mental IllnessA Beautiful MindA Beautiful MindA Bright Red ScreamA Casebook of Ethical Challenges in NeuropsychologyA Corner Of The UniverseA Lethal InheritanceA Mood ApartA Research Agenda for DSM-VA Slant of SunA War of NervesAbnormal Psychology in ContextADD-Friendly Ways to Organize Your LifeAddiction Recovery ToolsAdvance Directives in Mental HealthAggression and Antisocial Behavior in Children and AdolescentsAl-JununAlmost a PsychopathAlterations of ConsciousnessAm I Okay?American ManiaAmerican Psychiatric Publishing Textbook of Neuropsychiatry and Clinical NeurosciencesAn American ObsessionAngelheadAnger, Madness, and the DaimonicAnthology of a Crazy LadyApproaching NeverlandAs Nature Made HimAsylumAttention-Deficit Hyperactivity DisorderAttention-Deficit/Hyperactivity DisorderBeing Mentally Ill: A Sociological Theory Betrayal TraumaBetrayed as BoysBetter Than ProzacBetter Than WellBeyond AppearanceBeyond ReasonBinge No MoreBiological UnhappinessBipolar 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in AmericaCrazy Like UsCreating HysteriaCritical PsychiatryCruel CompassionCultural Assessment in Clinical PsychiatryCulture and Mental HealthCulture and Psychiatric DiagnosisCultures of NeurastheniaDaddy's GirlsDante's CureDarwinian PsychiatryDaughter of the Queen of ShebaDaughters of MadnessDeinstitutionalization And People With Intellectual DisabilitiesDelivered from DistractionDepression In Later LifeDepression SourcebookDepression-Free for LifeDescriptions and PrescriptionsDestructive Trends in Mental HealthDevil in the DetailsDiagnosis: SchizophreniaDiagnostic and Statistical Manual of Mental Disorders DSM-IV-TRDirty Filthy Love DVDDisorders Of DesireDisrupted LivesDissociative ChildrenDivided MindsDr. Andrew Weil's Guide to Optimum HealthDr. Weisinger's Anger Work-Out BookDSM-IV SourcebookDSM-IV-TR CasebookDSM-IV-TR in ActionDSM-IV-TR Mental DisordersE-TherapyEccentricsElectroshockEmergencies in Mental Health PracticeEmergency PsychiatryEmotional and Behavioral Problems of Young ChildrenEmotions and LifeEmpowering People with Severe Mental IllnessEssential PsychopharmacologyEssentials of Cas AssessmentEssentials of Wais-III AssessmentEthics and Values in PsychotherapyEthics in Mental Health ResearchEthics in Psychiatric ResearchEthics, Culture, and PsychiatryEverything In Its PlaceFamily Experiences With Mental IllnessFatigue as a Window to the BrainFear of IntimacyFinding Iris ChangFinding Meaning in the Experience of DementiaFlorid StatesFolie a DeuxFor the Love of ItForensic Nursing and Multidisciplinary Care of the Mentally Disordered OffenderFountain HouseFrom Madness to Mental HealthFrom Trauma to TransformationGandhi's WayGender and Its Effects on PsychopathologyGender and Mental HealthGenes, Environment, and PsychopathologyGetting Your Life BackGracefully InsaneGrieving Mental IllnessHandbook of AttachmentHandbook of DepressionHandbook of Self and IdentityHealing the SplitHerbs for the MindHidden SelvesHigh RiskHope and DespairHow Clients Make Therapy WorkHow People ChangeHow to Become a SchizophrenicHow We Think About DementiaHughes' Outline of Modern PsychiatryHumanizing MadnessHysterical MenHystoriesI Hate You-Don't Leave MeI Never Promised You a Rose GardenI Thought I Could FlyI'm CrazyImagining RobertImpulse Control DisordersIn Others' EyesIn Two MindsInsanityIntegrated Behavioral Health CareIntegrative MedicineIntegrative Mental Health CareIntuitionJust CheckingKarl JaspersKissing DoorknobsKundalini Yoga Meditation for Complex Psychiatric DisordersLaw and the BrainLaw, Liberty, and PsychiatryLegal and Ethical Aspects of HealthcareLiberatory PsychiatryLife at the BottomLife at the Texas State Lunatic Asylum, 1857-1997Life Is Not a Game of PerfectLithium for MedeaLiving Outside Mental IllnessLiving with AnxietyLiving With SchizophreniaLiving with SchizophreniaLiving Without Depression and Manic DepressionLost in the MirrorLove's ExecutionerLoving Someone With Bipolar DisorderMad in AmericaMad TravelersMad, Bad and SadMadhouseMadnessMadness at HomeMadness in Buenos AiresManaged Care ContractingMandated Reporting of Suspected Child AbuseManic Depression and CreativityMary BarnesMasters of the MindMeasuring PsychopathologyMedia MadnessMedicine As MinistryMelancholy And the Care of the SoulMemory, Brain, and BeliefMental HealthMental Health At The CrossroadsMental Health Issues in Lesbian, Gay, Bisexual, and Transgender Communities Mental Health MattersMental Health Policy in BritainMental Health Policy in BritainMental Health Professionals, Minorities and the PoorMental IllnessMental Illness and Your TownMental Illness, Medicine and LawMental SlaveryMindfulness in Plain EnglishModels of MadnessMothers Who Kill Their ChildrenMozart's Brain and the Fighter PilotMultifamily Groups in the Treatment of Severe Psychiatric DisordersMuses, Madmen, and ProphetsMyths of ChildhoodNapkin NotesNeural MisfireNew Hope For People With Bipolar DisorderNight Falls FastNo Enemies WithinNolaNormalNot CrazyNovember of the SoulOf Two MindsOn Being Normal and Other DisordersOn Our Own, TogetherOn The Stigma Of Mental IllnessOrigins of Human NatureOut of Its MindOut of the ShadowsOvercoming Compulsive HoardingPathologies of BeliefPathways through PainPersonal Recovery and Mental IllnessPersonality Disorder: Temperament or Trauma?Pillar of SaltPoints of ViewPoppy ShakespearePosttraumatic Stress DisorderPsychiatric Cultures ComparedPsychiatric Diagnosis and ClassificationPsychiatric Genetics and GenomicsPsychiatric Illness in WomenPsychiatrists and Traditional HealersPsychiatryPsychiatry and ReligionPsychiatry in SocietyPsychological Dimensions of the SelfPsychology and the MediaPsychopathia SexualisPsychopathologyPsychopathyPsychotic DepressionQuitting the Nairobi TrioRaising a Moody ChildRapid Cognitive TherapyRebuilding Shattered LivesReclaiming Soul in Health CareReclaiming the SoulRecollection, Testimony, and Lying in Early ChildhoodRecovery from SchizophreniaRecovery in Mental IllnessRedressing the EmperorRelational Mental HealthRemembering TraumaRepressed SpacesResearch Advances in Genetics and GenomicsRestricted AccessRethinking the DSMReviving OpheliaRewarding Specialties for Mental Health CliniciansSaints, Scholars, and Schizophrenics: Mental Illness in Rural IrelandSchizophreniaSchizophrenia RevealedSchizophrenia: A Scientific Delusion?Self-Determination Theory in the ClinicShunnedShynessSigns of SafetySilencing the VoicesSlackjawSocial Cognition and SchizophreniaSocial Inclusion of People with Mental IllnessSoul Murder RevisitedSounds from the Bell JarSpeaking Our MindsSpontaneous HealingStop PretendingStraight Talk about Psychological Testing for KidsStranger Than FictionStreet CrazyStudy Guide to the DSM-IV-TRSurviving Manic DepressionSurviving SchizophreniaSurviving SchizophreniaTaking Charge of ADHD, Revised EditionTaking the Fear Out of ChangingTalking Back to PsychiatryTarnationTeen LoveTelling Is Risky BusinessTelling SecretsThe Age of InsanityThe American Psychiatric Press Textbook of PsychiatryThe American Psychiatric Publishing Textbook Of Child And Adolescent PsychiatryThe Anger WorkbookThe Anorexic SelfThe Behavioral Medicine Treatment PlannerThe Betty Ford Center Book of AnswersThe Bipolar ChildThe Bipolar Disorder Survival GuideThe Body in PsychotherapyThe Borderline Personality Disorder Survival GuideThe Broken MirrorThe Burden of SympathyThe Cambridge Medical Ethics WorkbookThe Case for Pragmatic PsychologyThe Center Cannot HoldThe Chemical Dependence Treatment Documentation SourcebookThe Chemical Dependence Treatment PlannerThe Child and Adolescent Psychotherapy Treatment PlannerThe Clinical Child Documentation SourcebookThe Clinical Documentation SourcebookThe Complete Adult Psychotherapy Treatment PlannerThe Condition of MadnessThe Construction of Power and Authority in PsychiatryThe Couples Psychotherapy Treatment PlannerThe Criminal BrainThe Cultural Context of Health, Illness, and MedicineThe Day the Voices StoppedThe Death of PsychotherapyThe Depression WorkbookThe Difficult-to-Treat Psychiatric PatientThe Early Stages of SchizophreniaThe Employee Assistance Treatment PlannerThe Employee Assistance Treatment PlannerThe Epidemiology of SchizophreniaThe Essential Family Guide to Borderline Personality DisorderThe Essentials of New York Mental Health LawThe Ethical WayThe Evolution of Mental Health LawThe Explosive ChildThe Fall Of An IconThe Fasting GirlThe Forensic Documentation SourcebookThe Forgotten MournersThe Gift of Adult ADDThe Good EaterThe Green ParrotThe Healing Power of PetsThe Heart of AddictionThe Heroic ClientThe Insanity OffenseThe Invisible PlagueThe Last Time I Wore a DressThe Limits of Autobiography The LobotomistThe Madness of Our LivesThe Mark of ShameThe Meaning of AddictionThe Meaning of MindThe Medical AdvisorThe Mind/Mood Pill BookThe Most Solitary of AfflictionsThe Mozart EffectThe Naked Lady Who Stood on Her HeadThe Older Adult Psychotherapy Treatment PlannerThe OutsiderThe Pastoral Counseling Treatment PlannerThe PDR Family Guide to Natural Medicines & Healing TherapiesThe Places That Scare YouThe Plural SelfThe Problem of EvilThe Psychology of Religion and CopingThe Quiet RoomThe Real World Guide to Psychotherapy PracticeThe Right to Refuse Mental Health TreatmentThe Rise of Mental Health NursingThe Roots of the Recovery Movement in PsychiatryThe Savage GirlThe Self-Help SourcebookThe Talking CureThe Trick Is to Keep BreathingThe Unwell BrainThe Virtuous PsychiatristThe Way of TransitionThe Wing of MadnessThe Wisdom in FeelingTheoretical Evolutions in Person-Centered/Experiential TherapyTherapy's DelusionsTheraScribe 3.0 for WindowsThis is Madness TooThoughts Without a ThinkerThrough the Looking GlassTo Have Or To Be?Toxic PsychiatryTransforming MadnessTraumaTraumatic PastsTraumatic Relationships and Serious Mental DisordersTreating Affect PhobiaTreating Chronic and Severe Mental DisordersTreating Self-InjuryTreatment and Rehabilitation of Severe Mental IllnessTreatment Plans and Interventions for Depression and Anxiety DisordersTwinsUnderstanding and Treating Violent Psychiatric PatientsUnderstanding Child MolestersUnderstanding DepressionUnderstanding ParanoiaUnderstanding the Stigma of Mental IllnessUnderstanding Treatment Without ConsentUnholy MadnessUnspeakable Truths and Happy EndingsUsers and Abusers of PsychiatryViolence and Mental DisorderVoices of MadnessVoices of RecoveryVulnerability to PsychopathologyWarning: Psychiatry Can Be Hazardous to Your Mental HealthWashing My Life AwayWhen History Is a NightmareWhen Someone You Love Is BipolarWhen the Body SpeaksWhen Walls Become DoorwaysWitchcrazeWomen and Borderline Personality DisorderWomen and Mental IllnessWomen Who Hurt ThemselvesWomen's Mental HealthWrestling with the AngelYou Must Be DreamingYour Drug May Be Your ProblemYour Miracle Brain
So much has been published in
recent years, and so much of it in the mental health professions. Not all of
it has been exemplary, most of it entry level, much of it still tainted with a
century of blind speculation, and driven by hypotheses that would drive Scott Lilienfeld
to drink, or worse, publish another book slamming the pseudosciences and their
Not so this slim book from Kaplan
and Hammer. It may start off with a basic chapter, but that is where it stops
being for entry level practitioners in medicine and psychology.
The joke here is that when you are
tired of medicine, and want to leave the profession, you become a
psychiatrist. My registrars in their postgraduate years are overwhelmed when
we give them the Kandel, Schwartz and Jessell tome Principles of Neural
Science, or worse, Gazzaniga's magnificent doorstopper The New Cognitive
Neurosciences, with 24 sub-editors and 98 chapters in cognitive
I can't wait to show them this one.
Not that it is without flaws: after
all, the science presented here is only a few years old, so that any such book
is unlikely to be perfect, and as soon as the chapters are ready for print,
taking some years, then at publishing date, they are likely to be ancient
But as Heraclites said, you cannot
put your foot in the same river twice. So there are bound to be limitations.
In the brain behavior sciences, we
must examine why a particular patient presents with a particular behavior, at a
particular time in their lives.
This book sets out to map, for the
psychiatrist and other mental health professional with a biological streak in
them, how brain becomes mind, and what is wrong with the bad brain in various
After an introduction to functional
neural circuitry written by Salloway and Blitz, the book introduces the reader
to neural signaling pathways, written by Kaplan and Leite-Morris. The book
then covers schizophrenia (I would have preferred the term psychotic illnesses)
and then addiction, anxiety, depression, bipolar disorders, and then finally
Alzheimer's and dementia in general.
The first chapter is a nice one,
with really great diagrams that beg to be scanned and power-pointed, and I beg
the authors to CD Rom and sell them, they are so good for teaching purposes.
The authors examine visual signaling
(that was predictable) but then go on to the meat and vegetables of mental
health, namely the functional organization of the limbic system, prefrontal
cortex, frontal-subcortical-thalamic circuits, and finally the brainstem
systems, all focusing on how information is processed and behaviour regulated.
Add to this volume things from Russ Barkley on the evolution of
self-regulation, use Miller and Cummings' work on subcortical frontal
conditions, and the students are gearing up for Kandel and Gazzaniga. A touch
of Damasio, and the first year registrars will begin to see the DSM-IV-TR in
stark focus. Each section of this first chapter contains some reference to
where the structures are, how they connect to other areas, what their primary
role in the brain must therefore be, and how they do this via neurochemical
pathways and how pathology emerges from disruption or dysfunction. As the
author's caution at the end of the chapter, if the brain were that simple that
we could understand it, then our observing brains would lack the capacity to
understand these concepts, a nice tautology, I think first pointed out by Emerson
The conclusions to chapter two
likewise come with caveats. Much research is needed to determine which
molecular changes in mesocorticolimbic pathways are responsible for the effects
of drugs, and again, the pathways are part of a dynamic homeostatic second
order cybernetic system that cannot easily be illuminated on with regard to the
linear intervention of medication. The chapter nevertheless charts, in simple
terms, the physical highways in the brain and the chemical messenger systems
that enable such homeostasis, by elucidating the signal transduction mechanism
as far as we know them. A nice side to this book is that this chapter, like
others, is kept short and tight, only 30 pages, and reader exhaustion is
avoided. Length is not strength after all, and this does nicely.
And of course, while this book does
all that, it refers to everyone present and gone in the literature from Kandel,
to the luckless Goldman-Rakic.
Heckers and Goff bravely take on
the review of schizophrenia, and waste a few pages on history and subtypes
which probably is unnecessary: anyone using this book would know all that, and
the subtypes are not neurologically helpful anyway. But the rest is sheer
bliss to read, with detailed explanations of every possible sort, including all
the neurotransmitters that are necessarily connected, and not just the
monoamines, but the glutamates of the world are also here, with easily 200
references packed into the few pages allowed for this chapter, a monumental,
but tiny work. Again, there is so much more now in 2003, just a year later
than publication date, but this is good stuff to read and absorb. It is all
made so easier by crisp and clear prose, and tight editing.
Speaking of the editor, Hammer
himself takes on the task of explaining neural circuitry and signaling in
addiction, addressing the paradigm shift that forced the entry of the book's focused
topics into addiction studies. No longer seen as voluntary self-administration
behavior, addiction is now seen as an understandable offshoot of normal reward
seeking behavior become brain disease, with its focus on the dopamine systems
of the subcortex. Predictably the words nucleus and accumbens are paired, and
early on emerge in the discussion of neural circuitry. This fourth chapter is
complex and dense, and takes some reading for the implications to sink in. At
face value, this is about reward seeking behavior, but its implications go much
wider afield, and relate easily to social competition and learning theories in
Kent, Sullivan and Rauch embark on
anxiety, and again, tight writing style and clear but intricate diagrams make
it accessible, if not simple. For instance, a really useful diagram on page 137
embarks on the task of making the homeostatic feedback loops of the cortico-thalamo-cortical
circuits understandable, and relating this to OCD, and by implication, if you
read Scandanavian Nobel Prize laureate's work for fun, related conditions such
as ADHD as well. Again, the fingers itch for the scanner and a bit of diagram
Marek and Duman cope with
depression in the same way, again with tight prose and good diagrams. Despite
the age of the book, now out for a year, the work on brain-derived neurotrophic
factor is up to date, as is the information on the neurodegeneration of frontal
and limbic areas.
Sassi and Soares take on bipolar
disorder. In 13 pages. Either little is known, or they write as tightly as
the others. Nine pages of references suggest the latter.
Nixon works on Alzheimer's and
dementia, and certainly concentrates on the former, since much more is known,
but the later comments on the Chromosome 17 taupathies is a little thin, and
summarizes what one will find in other tomes, such as Burns and Levy.
A noticeable and only failure of
the book is the absence of a collated index of authors, although of course each
chapter has its own. The subject index is comprehensive.
The only thing to do is buy this
book, prescribe it to students, and honor it for what it is: good.
© 2003 Roy Sugarman
PhD, Clinical Lecturer in Psychiatry, Adelaide University, Senior Cinical
Neuropsychologist, Royal Adelaide Hospital Glenside Campus Extended Care.